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10.5935/1518-0557.20240073 14 ChowdhuryM

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Glutathione in particular is vulnerable to breakdown in the digestive tract before it reaches circulation, which is part of why liposomal and other absorption-focused formats have become common

DOI: 10.1038/nature22056

Nrf1 knockout mice die in utero but fetal hepatocytes and embryonal fibroblasts have lower GSH levels and are more susceptible to oxidative stress [107,114]